Do not adjust your dose of LEVITRA without speaking with your health care provider. Your medical doctor may well reduce your dose or increase your dose, based upon how One's body reacts to LEVITRA.
Keep a listing of all of the solutions you use (which include prescription/nonprescription medication and herbal solutions) and share it together with your health practitioner and pharmacist. Don't start out, quit, or alter the dosage of any medicines with out your physician's acceptance.
Usually consult your healthcare supplier to make certain the knowledge shown on this webpage applies to your own situations.
Administration of LEVITRA with nitrates (possibly consistently and/or intermittently) and nitric oxide donors is contraindicated [see CLINICAL PHARMACOLOGY]. In line with the effects of PDE5 inhibition within the nitric oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors, like LEVITRA, may well potentiate the hypotensive consequences of nitrates.
Get crisis clinical help if you have indications of an allergic response to Levitra: hives; hard respiration; swelling of one's face, lips, tongue, or throat.
The maximum dose of LEVITRA for which human details can be obtained is an individual 120 mg dose administered to healthy male volunteers. Nearly all of these topics knowledgeable reversible back agony/myalgia and/or “irregular vision.
Ritonavir (600 mg b.i.d.) co-administered with LEVITRA five mg resulted inside a 49-fold boost in vardenafil AUC along with a 13fold rise in vardenafil Cmax. The conversation is a consequence of blocking hepatic metabolism of vardenafil by ritonavir, a HIV protease inhibitor plus a really potent CYP3A4 inhibitor, which also inhibits CYP2C9.
LEVITRA can cause your blood pressure level to fall instantly to an unsafe level if it is taken with specified other medicines. Which has a sudden drop in blood pressure level, you could potentially get dizzy, faint, click here or have a heart assault or stroke.
There aren't any managed clinical facts on the safety or efficacy of vardenafil in the subsequent individuals; and as a consequence its use isn't proposed until finally further more details is out there: unstable angina; hypotension (resting systolic blood pressure of a hundred and seventy/110 mmHg); modern history of stroke, daily life-threatening arrhythmia, or myocardial infarction (throughout the final six months); severe cardiac failure.
An appropriate time interval following dosing of LEVITRA for that Secure administration of nitrates or nitric oxide donors hasn't been established.
Low amounts of potassium or magnesium inside the blood may also boost your chance of QT prolongation. This danger may perhaps enhance if you use sure medicines (such as diuretics/"h2o capsules") or if you have ailments like intense sweating, diarrhea, or vomiting. Talk to your health practitioner about utilizing vardenafil properly.
Discuss with clients the possible cardiac hazard of sexual action for patients with preexisting cardiovascular possibility aspects.
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Concomitant use with nitrates and nitric oxide donors in any form is contraindicated [see CONTRAINDICATIONS].